Microwave-Assisted Resolution of α-Lipoic Acid Catalyzed by an Ionic Liquid Co-Lyophilized Lipase.

نویسندگان

  • Ning Liu
  • Lei Wang
  • Zhi Wang
  • Liyan Jiang
  • Zhuofu Wu
  • Hong Yue
  • Xiaona Xie
چکیده

The combination of the ionic liquid co-lyophilized lipase and microwave irradiation was used to improve enzyme performance in enantioselective esterification of α-lipoic acid. Effects of various reaction conditions on enzyme activity and enantioselectivity were investigated. Under optimal condition, the highest enantioselectivity (E = 41.2) was observed with a high enzyme activity (178.1 μmol/h/mg) when using the ionic liquid co-lyophilized lipase with microwave assistance. Furthermore, the ionic liquid co-lyophilized lipase exhibited excellent reusability under low power microwave.

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عنوان ژورنال:
  • Molecules

دوره 20 6  شماره 

صفحات  -

تاریخ انتشار 2015